GENOMIC ALTERATION DURING METASTASIS OF LUNG ADENOCARCINOMA

Genomic Alteration During Metastasis of Lung Adenocarcinoma

Background/Aims: Recurrent gene mutation has been identified by the analysis of exonic DNA from lung adenocarcinoma, but its progression has not been extensively profiled.The investigation of the mutational landscape of tumors provides new insights into cancer genome evolution and further discovers the interplay of somatic mutation, adaptation of c

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Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator

Constrictive vascular remodeling limiting blood flow, as well as compensatory outward remodeling, has been observed in many cardiovascular diseases; however, the underlying mechanisms regulating the remodeling response of the vessels remain unclear.Plasminogen activators (PA) are involved in many of the processes of vascular remodeling.We have show

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